Cleidocranial dysplasia: case report of three siblings.

ABSTRACT:

Background

A family case report of cleidocranial dysplasia (CCD) with varied manifestations from father to three siblings is presented. CCD ( MIM # 119600) is a rare autosomal dominant skeletal dysplasia caused by CBAF1 gene ( OMIM 600211) with a wide range of variability. In all the cases generalized dysplasia in bone, prolonged retention of primary teeth and delayed eruption of permanent teeth were evident. Interestingly, there were no supernumerary teeth present. There was mandibular prognathism which was intercepted by occipital chin cup therapy.

Aims and objective

To present the clinical manifestations, diagnostic imaging and treatment modalities along with dermatoglyphics in CCD patients.

Conclusion

Cleidocranial dysplasia is an uncommon disorder however its cli

SUBMITTER: Mathur R 

PROVIDER: S-EPMC4086567 | biostudies-literature | 2009 May

REPOSITORIES: biostudies-literature