Characterization of peripheral nerve sheath tumors with 3T proton MR spectroscopy.

ABSTRACT:

Background and purpose

The characterization of peripheral nerve sheath tumors is challenging. The purpose here was to investigate the diagnostic value of quantitative proton MR spectroscopy at 3T for the characterization of peripheral nerve sheath tumors as benign or malignant, compared with PET.

Materials and methods

Twenty participants with 24 peripheral nerve sheath tumors underwent MR spectroscopy by use of a point-resolved sequence (TE, 135 ms). Six voxels were placed in 4 histologically proven malignant peripheral nerve sheath tumors and 22 voxels in 20 benign peripheral nerve sheath tumors (9 histologically proven, 11 with documented stability). The presence or absence of a trimethylamine signal was evaluated, the trimethylamine concentration estimated by use of phant

SUBMITTER: Fayad LM 

PROVIDER: S-EPMC4086645 | biostudies-literature | 2014 May

REPOSITORIES: biostudies-literature