Adaptive introgression between Anopheles sibling species eliminates a major genomic island but not reproductive isolation.

ABSTRACT: Adaptive introgression can provide novel genetic variation to fuel rapid evolutionary responses, though it may be counterbalanced by potential for detrimental disruption of the recipient genomic background. We examine the extent and impact of recent introgression of a strongly selected insecticide-resistance mutation (Vgsc-1014F) located within one of two exceptionally large genomic islands of divergence separating the Anopheles gambiae species pair. Here we show that transfer of the Vgsc mutation results in homogenization of the entire genomic island region (~1.5% of the genome) between species. Despite this massive disruption, introgression is clearly adaptive with a dramatic rise in frequency of Vgsc-1014F and no discernable impact on subsequent reproductive isolation between species. O

SUBMITTER: Clarkson CS 

PROVIDER: S-EPMC4086683 | biostudies-literature | 2014 Jun

REPOSITORIES: biostudies-literature