Randomized clinical trial of self versus clinical administration of subcutaneous depot medroxyprogesterone acetate.

ABSTRACT:

Objectives

To evaluate feasibility, acceptability, continuation, and trough serum levels following self-administration of subcutaneous (sc) depot medroxyprogesterone acetate (DMPA).

Study design

Women presenting to a family planning clinic to initiate, restart or continue DMPA were offered study entry. Participants were randomized in a 2:1 ratio to self- or clinician administered sc DMPA 104 mg. Those randomized to self-administration were taught to self-inject and were supervised in performing the initial injection; they received printed instructions and a supply of contraceptive injections for home use. Participants randomized to clinician administration received usual care. Continued DMPA use was assessed by self-report and trough medroxyprogesterone acetate levels at 6 a

SUBMITTER: Beasley A 

PROVIDER: S-EPMC4086940 | biostudies-literature | 2014 May

REPOSITORIES: biostudies-literature