Quality of life and toxicity from passively scattered and spot-scanning proton beam therapy for localized prostate cancer.

ABSTRACT:

Purpose

To report quality of life (QOL)/toxicity in men treated with proton beam therapy for localized prostate cancer and to compare outcomes between passively scattered proton therapy (PSPT) and spot-scanning proton therapy (SSPT).

Methods and materials

Men with localized prostate cancer enrolled on a prospective QOL protocol with a minimum of 2 years' follow-up were reviewed. Comparative groups were defined by technique (PSPT vs SSPT). Patients completed Expanded Prostate Cancer Index Composite questionnaires at baseline and every 3-6 months after proton beam therapy. Clinically meaningful differences in QOL were defined as ≥0.5 × baseline standard deviation. The cumulative incidence of modified Radiation Therapy Oncology Group grade ≥2 gastrointestinal (GI) or genitourin

SUBMITTER: Pugh TJ 

PROVIDER: S-EPMC4086944 | biostudies-literature | 2013 Dec

REPOSITORIES: biostudies-literature