Time for a neonatal-specific consensus definition for sepsis.

ABSTRACT:

Objective

To review the accuracy of the pediatric consensus definition of sepsis in term neonates and to determine the definition of neonatal sepsis used.

Study selection

The review focused primarily on pediatric literature relevant to the topic of interest.

Conclusions

Neonatal sepsis is variably defined based on a number of clinical and laboratory criteria that make the study of this common and devastating condition very difficult. Diagnostic challenges and uncertain disease epidemiology necessarily result from a variable definition of disease. In 2005, intensivists caring for children recognized that as new drugs became available, children would be increasingly studied and thus, pediatric-specific consensus definitions were needed. Pediatric sepsis criteria are not

SUBMITTER: Wynn JL 

PROVIDER: S-EPMC4087075 | biostudies-literature | 2014 Jul

REPOSITORIES: biostudies-literature