High-resolution reduced field of view diffusion tensor imaging using spatially selective RF pulses.

ABSTRACT:

Purpose

Diffusion tensor imaging (DTI) plays a vital role in identifying white matter fiber bundles. Achievable imaging resolution and imaging time demands remain the major challenges in detecting small fiber bundles with current clinical DTI sequences.

Methods

A novel reduced field of view ultra-high-resolution DTI technique named eZOOM (elliptically refocused zonally oblique multislice) was developed. A small circular disk was imaged using spatially selective radiofrequency (RF) pulses, reducing the imaging matrix size. The frequency profile of the spectral-spatial refocusing RF pulse provided intrinsic fat suppression, eliminating the need for fat saturation pulses.

Results

Multislice DTI at a resolution of 0.35 × 0.35 mm in a celery fiber phantom was successfully

SUBMITTER: Gaggl W 

PROVIDER: S-EPMC4090294 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature