Late outcomes of a randomized trial of high-frequency oscillation in neonates.

ABSTRACT:

Background

Results from an observational study involving neonates suggested that high-frequency oscillatory ventilation (HFOV), as compared with conventional ventilation, was associated with superior small-airway function at follow-up. Data from randomized trials are needed to confirm this finding.

Methods

We studied 319 adolescents who had been born before 29 weeks of gestation and had been enrolled in a multicenter, randomized trial that compared HFOV with conventional ventilation immediately after birth. The trial involved 797 neonates, of whom 592 survived to hospital discharge. We compared follow-up data from adolescents who had been randomly assigned to HFOV with follow-up data from those who had been randomly assigned to conventional ventilation, with respect to lung

SUBMITTER: Zivanovic S 

PROVIDER: S-EPMC4090580 | biostudies-literature | 2014 Mar

REPOSITORIES: biostudies-literature