Hydroxyl-directed stereoselective diboration of alkenes.

ABSTRACT: An alkoxide-catalyzed directed diboration of alkenyl alcohols is described. This reaction occurs in a stereoselective fashion and is demonstrated with cyclic and acyclic homoallylic and bishomoallylic alcohol substrates. After oxidation, the reaction generates 1,2-diols such that the process represents a method for the stereoselective directed dihydroxylation of alkenes.

SUBMITTER: Blaisdell TP 

PROVIDER: S-EPMC4091278 | biostudies-literature | 2014 Jul

REPOSITORIES: biostudies-literature