Relationship between polymorphisms in beta -2 adrenergic receptor gene and ischemic stroke in North Indian Population: a hospital based case control study.

ABSTRACT:

Background

Stroke is a multi-factorial disease and influenced by both genetic and environmental factors. The purpose of the present case control study was to check the relationship between beta-2 adrenergic receptor (ADRB2) polymorphism and ischemic stroke in North Indian Population.

Methods

In a hospital based case control study, patients with ischemic stroke and control subjects from outpatient department and neurology ward of All India Institute of Medical Sciences New Delhi. Genotyping was performed by using Polymerase chain reaction-Restriction fragment length polymorphism. Frequency distributions of genotypes and alleles were compared between cases and controls using multivariate logistic regression.

Results

In this study, 224 patients and 224 age-and sex-matche

SUBMITTER: Kumar A 

PROVIDER: S-EPMC4091742 | biostudies-literature | 2014 Jun

REPOSITORIES: biostudies-literature