Activation of the Arabidopsis thaliana immune system by combinations of common ACD6 alleles.

ABSTRACT: A fundamental question in biology is how multicellular organisms distinguish self and non-self. The ability to make this distinction allows animals and plants to detect and respond to pathogens without triggering immune reactions directed against their own cells. In plants, inappropriate self-recognition results in the autonomous activation of the immune system, causing affected individuals to grow less well. These plants also suffer from spontaneous cell death, but are at the same time more resistant to pathogens. Known causes for such autonomous activation of the immune system are hyperactive alleles of immune regulators, or epistatic interactions between immune regulators and unlinked genes. We have discovered a third class, in which the Arabidopsis thaliana immune system is activated b

SUBMITTER: Todesco M 

PROVIDER: S-EPMC4091793 | biostudies-literature | 2014 Jul

REPOSITORIES: biostudies-literature