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Rocaglamide, silvestrol and structurally related bioactive compounds from Aglaia species.


ABSTRACT: Covering: 2006 to 2013. Investigations on the chemistry and biology of rocaglamide, silvestrol and structurally related bioactive compounds from Aglaia species during the period 2006-2013 are reviewed. Included are new phytochemical studies of naturally occurring rocaglamide derivatives, an update on synthetic methods for cyclopenta[b]benzofurans, and a description of the recent biological evaluation and mechanism-of-action studies on compounds of this type.

SUBMITTER: Pan L 

PROVIDER: S-EPMC4091845 | biostudies-literature | 2014 Jul

REPOSITORIES: biostudies-literature

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Rocaglamide, silvestrol and structurally related bioactive compounds from Aglaia species.

Pan Li L   Woodard John L JL   Lucas David M DM   Fuchs James R JR   Kinghorn A Douglas AD  

Natural product reports 20140502 7


Covering: 2006 to 2013. Investigations on the chemistry and biology of rocaglamide, silvestrol and structurally related bioactive compounds from Aglaia species during the period 2006-2013 are reviewed. Included are new phytochemical studies of naturally occurring rocaglamide derivatives, an update on synthetic methods for cyclopenta[b]benzofurans, and a description of the recent biological evaluation and mechanism-of-action studies on compounds of this type. ...[more]

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