Ontology highlight
ABSTRACT:
SUBMITTER: Nettiksimmons J
PROVIDER: S-EPMC4092059 | biostudies-literature | 2014 Sep
REPOSITORIES: biostudies-literature
Nettiksimmons Jasmine J DeCarli Charles C Landau Susan S Beckett Laurel L
Alzheimer's & dementia : the journal of the Alzheimer's Association 20140110 5
<h4>Background</h4>Previous work examining normal controls from the Alzheimer's Disease Neuroimaging Initiative (ADNI) identified substantial biological heterogeneity. We hypothesized that ADNI mild cognitive impairment (MCI) subjects would also exhibit heterogeneity with possible clinical implications.<h4>Methods</h4>ADNI subjects diagnosed with amnestic MCI (n=138) were clustered based on baseline magnetic resonance imaging, cerebrospinal fluid, and serum biomarkers. The clusters were compared ...[more]