The transcriptomic profile of peripheral blood nuclear cells in dogs with heart failure.

ABSTRACT:

Background

In recent years advances have been made in the investigative methods of molecular background of canine heart disease. Studies have been conducted to identify specific genes which, when pathologically expressed, could lead to the dysfunction of the canine heart or are correlated with heart failure. For this purpose genome wide microarray experiments on tissues from failing hearts have been performed. In the presented study a whole genome microarray analysis was used for the first time to describe the transcription profile of peripheral blood nuclear cells in dogs with heart failure. Dogs with recognized heart disease were classified according the ISACHC (International Small Animal Cardiac Health Council) classification scheme as class 1 (asymptomatic)--13 dogs, class 2 (m

SUBMITTER: Hulanicka M 

PROVIDER: S-EPMC4092214 | biostudies-literature | 2014 Jun

REPOSITORIES: biostudies-literature