Detection of genome-wide copy number variations in two chicken lines divergently selected for abdominal fat content.

ABSTRACT:

Background

The chicken (Gallus gallus) is an important model organism that bridges the evolutionary gap between mammals and other vertebrates. Copy number variations (CNVs) are a form of genomic structural variation widely distributed in the genome. CNV analysis has recently gained greater attention and momentum, as the identification of CNVs can contribute to a better understanding of traits important to both humans and other animals. To detect chicken CNVs, we genotyped 475 animals derived from two broiler chicken lines divergently selected for abdominal fat content using chicken 60 K SNP array, which is a high-throughput method widely used in chicken genomics studies.

Results

Using PennCNV algorithm, we detected 438 and 291 CNVs in the lean and fat lines, respectively, co

SUBMITTER: Zhang H 

PROVIDER: S-EPMC4092215 | biostudies-literature | 2014 Jun

REPOSITORIES: biostudies-literature