Profile of whole blood gene expression following immune stimulation in a wild passerine.

ABSTRACT:

Background

Immunoecology aims to explain variation among hosts in the strength and efficacy of immunological defences in natural populations. This requires development of biomarkers of the activation of the immune system so that they can be collected non-lethally and sampled from small amounts of easily obtainable tissue. We used transcriptome profiling in wild greenfinches (Carduelis chloris) to detect whole blood transcripts that most profoundly indicate upregulation of antimicrobial defences during acute phase response. The more general aim of this study was to obtain a functional annotation of a substantial portion of the greenfinch transcriptome that would enable to gain access to more specific genomic tools in subsequent studies. The birds received either bacterial lipopolysa

SUBMITTER: Meitern R 

PROVIDER: S-EPMC4092216 | biostudies-literature | 2014 Jun

REPOSITORIES: biostudies-literature