Advances and new perspectives in the treatment of metastatic colon cancer.

ABSTRACT: During the last decade we have witnessed an unprecedented outburst of new treatment approaches for the management of metastatic colon cancer. Anti-angiogenic drugs, epidermal growth factor receptor blockers and multi-kinase inhibitors have all resulted in small but consistent improvement in clinical outcomes. However, this progress has paradoxically leaded us into new challenges. In many cases the clinical development was done in parallel and the lack of head-to-head comparison evolved into circumstances where several valid new "standards of care" are available. Even though desirable in essence, the availability of many options as well as different possible combinations frequently leaves the busy clinician in the difficult situation of having to choose between one or the other, sometimes w

SUBMITTER: Recondo G 

PROVIDER: S-EPMC4092338 | biostudies-literature | 2014 Jul

REPOSITORIES: biostudies-literature