Prognostic models for high and low ovarian responses in controlled ovarian stimulation using a GnRH antagonist protocol.

ABSTRACT:

Study question

Can predictors of low and high ovarian responses be identified in patients undergoing controlled ovarian stimulation (COS) in a GnRH antagonist protocol?

Summary answer

Common prognostic factors for high and low ovarian responses were female age, antral follicle count (AFC) and basal serum FSH and LH.

What is known already

Predictors of ovarian response have been identified in GnRH agonist protocols. With the introduction of GnRH antagonists to prevent premature LH rises during COS, and the gradual shift in use of long GnRH agonist to short GnRH antagonist protocols, there is a need for data on the predictability of ovarian response in GnRH antagonist cycles.

Study design, size, duration

A retrospective analysis of data from the Engage trial and

SUBMITTER: Broekmans FJ 

PROVIDER: S-EPMC4093990 | biostudies-literature | 2014 Aug

REPOSITORIES: biostudies-literature