Uncinate fasciculus fractional anisotropy correlates with typical use of reappraisal in women but not men.

ABSTRACT: Emotion regulation refers to strategies through which individuals influence their experience and expression of emotions. Two typical strategies are reappraisal, a cognitive strategy for reframing the context of an emotional experience, and suppression, a behavioral strategy for inhibiting emotional responses. Functional neuroimaging studies have revealed that regions of the prefrontal cortex modulate amygdala reactivity during both strategies, but relatively greater downregulation of the amygdala occurs during reappraisal. Moreover, these studies demonstrated that engagement of this modulatory circuitry varies as a function of gender. The uncinate fasciculus is a major structural pathway connecting regions of the anterior temporal lobe, including the amygdala to inferior frontal regions, e

SUBMITTER: Zuurbier LA 

PROVIDER: S-EPMC4094171 | biostudies-literature | 2013 Jun

REPOSITORIES: biostudies-literature