Effects of whole and refined grains in a weight-loss diet on markers of metabolic syndrome in individuals with increased waist circumference: a randomized controlled-feeding trial.

ABSTRACT:

Background

Higher whole-grain (WG) intake is associated with a lower prevalence of metabolic syndrome (MetS); however, there is inconsistent clinical evidence with regard to the benefit of WGs compared with refined grains (RGs) on MetS.

Objective

We hypothesized that consuming WGs in the place of RGs would improve MetS criteria in individuals with or at risk of MetS.

Design

A randomized, controlled, open-label parallel study was conducted in 50 overweight and obese individuals with increased waist circumference and one or more other MetS criteria. Participants consumed a controlled weight-loss diet containing either WG or RG (control) products for 12 wk. Body composition, MetS criteria and related markers, and plasma alkylresorcinols (compliance marker of WG intake) w

SUBMITTER: Harris Jackson K 

PROVIDER: S-EPMC4095661 | biostudies-literature | 2014 Aug

REPOSITORIES: biostudies-literature