Functional connectivity during modulation of tinnitus with orofacial maneuvers.

ABSTRACT:

Objective

To determine changes in cortical neural networks as defined by resting-state functional connectivity magnetic resonance imaging during voluntary modulation of tinnitus with orofacial maneuvers.

Study design

Cross-sectional study.

Setting

Academic medical center.

Subjects and methods

Participants were scanned during the maneuver and also at baseline to serve as their own control. The authors chose, a priori, 58 seed regions to evaluate previously described cortical neural networks by computing temporal correlations between all seed region pairs. Seed regions whose correlations significantly differed between rest and maneuver (P < .05, uncorrected) entered into a second-stage analysis of computing the correlation coefficient between the seed region and

SUBMITTER: Lee MH 

PROVIDER: S-EPMC4095801 | biostudies-literature | 2012 Oct

REPOSITORIES: biostudies-literature