The dynamics of cortical neuronal activity in the first minutes after spontaneous awakening in rats and mice.

ABSTRACT:

Study objective

Upon awakening from sleep, a fully awake brain state is not reestablished immediately, but the origin and physiological properties of the distinct brain state during the first min after awakening are unclear. To investigate whether neuronal firing immediately upon arousal is different from the remaining part of the waking episode, we recorded and analyzed the dynamics of cortical neuronal activity in the first 15 min after spontaneous awakenings in freely moving rats and mice.

Design

Intracortical recordings of the local field potential and neuronal activity in freely-moving mice and rats.

Setting

Basic sleep research laboratory.

Patients or participants

WKY adult male rats, C57BL/6 adult male mice.

Interventions

N/A.

Measurements and

SUBMITTER: Vyazovskiy VV 

PROVIDER: S-EPMC4096203 | biostudies-literature | 2014 Aug

REPOSITORIES: biostudies-literature