Low-frequency pulsed electromagnetic fields significantly improve time of closure and proliferation of human tendon fibroblasts.

ABSTRACT:

Background

The promotion of the healing process following musculoskeletal injuries comprises growth factor signalling, migration, proliferation and apoptosis of cells. If these processes could be modulated, the healing of tendon tissue may be markedly enhanced. Here, we report the use of the Somagen™ device, which is certified for medical use according to European laws. It generates low-frequency pulsed electromagnetic fields that trigger effects of a nature that are yet to be determined.

Methods

A 1.5-cm wide, linear scrape was introduced into patellar tendon fibroblast cultures (N = 5 donors). Treatment was carried out every second day. The regimen was applied three times in total with 30 minutes comprising pulsed electromagnetic field packages with two fundamental frequen

SUBMITTER: Seeliger C 

PROVIDER: S-EPMC4096547 | biostudies-literature | 2014 Jul

REPOSITORIES: biostudies-literature