Intracranial pressure in unresponsive chronic migraine.

ABSTRACT: To assess the prevalence and possible pathogenetic involvement of raised intracranial pressure in patients presenting with unresponsive chronic migraine (CM), we evaluated the intracranial opening pressure (OP) and clinical outcome of a single cerebrospinal fluid withdrawal by lumbar puncture in 44 consecutive patients diagnosed with unresponsive chronic/transformed migraine and evidence of sinus stenosis at magnetic resonance venography. The large majority of patients complained of daily or near-daily headache. Thirty-eight (86.4%) had an OP >200 mmH2O. Lumbar puncture-induced normalization of intracranial pressure resulted in prompt remission of chronic pain in 34/44 patients (77.3%); and an episodic pattern of headache was maintained for 2, 3 and 4 months in 24 (54.6%), 20 (45.4%) and 1

SUBMITTER: De Simone R 

PROVIDER: S-EPMC4097326 | biostudies-literature | 2014 Jul

REPOSITORIES: biostudies-literature