Racial and regional differences in venous thromboembolism in the United States in 3 cohorts.

ABSTRACT:

Background

Blacks are thought to have a higher risk of venous thromboembolism (VTE) than whites. However, prior studies are limited to administrative databases that lack specific information on VTE risk factors or have limited geographic scope.

Methods and results

We ascertained VTE from 3 prospective studies: the Atherosclerosis Risk in Communities Study (ARIC), the Cardiovascular Health Study (CHS), and the Reasons for Geographic and Racial Differences in Stroke study (REGARDS). We tested the association of race with VTE using Cox proportional hazard models adjusted for VTE risk factors. Over 438 090 person-years, 916 incident VTE events (302 in blacks) occurred in 51 149 individuals (17 318 blacks) who were followed up. In risk factor-adjusted models, blacks had a higher

SUBMITTER: Zakai NA 

PROVIDER: S-EPMC4098668 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature