Large-scale cell production of stem cells for clinical application using the automated cell processing machine.

ABSTRACT:

Background

Cell-based regeneration therapies have great potential for application in new areas in clinical medicine, although some obstacles still remain to be overcome for a wide range of clinical applications. One major impediment is the difficulty in large-scale production of cells of interest with reproducibility. Current protocols of cell therapy require a time-consuming and laborious manual process. To solve this problem, we focused on the robotics of an automated and high-throughput cell culture system. Automated robotic cultivation of stem or progenitor cells in clinical trials has not been reported till date. The system AutoCulture used in this study can automatically replace the culture medium, centrifuge cells, split cells, and take photographs for morphological assessme

SUBMITTER: Kami D 

PROVIDER: S-EPMC4101824 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature