CeleST: computer vision software for quantitative analysis of C. elegans swim behavior reveals novel features of locomotion.

ABSTRACT: In the effort to define genes and specific neuronal circuits that control behavior and plasticity, the capacity for high-precision automated analysis of behavior is essential. We report on comprehensive computer vision software for analysis of swimming locomotion of C. elegans, a simple animal model initially developed to facilitate elaboration of genetic influences on behavior. C. elegans swim test software CeleST tracks swimming of multiple animals, measures 10 novel parameters of swim behavior that can fully report dynamic changes in posture and speed, and generates data in several analysis formats, complete with statistics. Our measures of swim locomotion utilize a deformable model approach and a novel mathematical analysis of curvature maps that enable even irregular patterns and dyna

SUBMITTER: Restif C 

PROVIDER: S-EPMC4102393 | biostudies-literature | 2014 Jul

REPOSITORIES: biostudies-literature