Development and validation of intracranial thrombus segmentation on CT angiography in patients with acute ischemic stroke.

ABSTRACT:

Background and purpose

Thrombus characterization is increasingly considered important in predicting treatment success for patients with acute ischemic stroke. The lack of intensity contrast between thrombus and surrounding tissue in CT images makes manual delineation a difficult and time consuming task. Our aim was to develop an automated method for thrombus measurement on CT angiography and validate it against manual delineation.

Materials and methods

Automated thrombus segmentation was achieved using image intensity and a vascular shape prior derived from the segmentation of the contralateral artery. In 53 patients with acute ischemic stroke due to proximal intracranial arterial occlusion, automated length and volume measurements were performed. Accuracy was assessed by co

SUBMITTER: Santos EM 

PROVIDER: S-EPMC4102487 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature