Assessing the performance of the Framingham Stroke Risk Score in the reasons for geographic and racial differences in stroke cohort.

ABSTRACT:

Background and purpose

The most well-known stroke risk score is the Framingham Stroke Risk Score (FSRS), which was developed during the higher stroke risk period of the 1990s and has not been validated for blacks. We assessed the performance of the FSRS among participants in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) study to determine whether it is useful in both blacks and whites.

Methods

Expected annualized stroke rates from the FSRS were compared with observed stroke rates overall and within strata defined by FSRS risk factors (age, sex, systolic blood pressure, use of antihypertensive medications, diabetes mellitus, smoking, atrial fibrillation, left ventricular hypertrophy, and prevalent coronary heart disease).

Results

Among 27 748 pa

SUBMITTER: McClure LA 

PROVIDER: S-EPMC4102650 | biostudies-literature | 2014 Jun

REPOSITORIES: biostudies-literature