Is catechol-o-methyltransferase gene polymorphism a risk factor in the development of premenstrual syndrome?

ABSTRACT:

Objective

The objective of this study was to investigate whether there was a correlation between catechol-o-methyltransferase (COMT) gene polymorphism, which is believed to play a role in the etiology of psychotic disorders, and premenstrual syndrome (PMS).

Methods

Fifty-three women with regular menstrual cycles, aged between 18 and 46 years and diagnosed with PMS according to the American Congress of Obstetrics and Gynecology criteria were included in this study as the study group, and 53 healthy women having no health problems were selected as the controls. Venous blood was collected from all patients included in the study and kept at -18℃ prior to analysis.

Results

There was no significant difference between the groups in terms of demographic features such as age,

SUBMITTER: Deveci EO 

PROVIDER: S-EPMC4102691 | biostudies-literature | 2014 Jun

REPOSITORIES: biostudies-literature