PRADA: pipeline for RNA sequencing data analysis.

ABSTRACT:

Summary

Technological advances in high-throughput sequencing necessitate improved computational tools for processing and analyzing large-scale datasets in a systematic automated manner. For that purpose, we have developed PRADA (Pipeline for RNA-Sequencing Data Analysis), a flexible, modular and highly scalable software platform that provides many different types of information available by multifaceted analysis starting from raw paired-end RNA-seq data: gene expression levels, quality metrics, detection of unsupervised and supervised fusion transcripts, detection of intragenic fusion variants, homology scores and fusion frame classification. PRADA uses a dual-mapping strategy that increases sensitivity and refines the analytical endpoints. PRADA has been used extensively and succe

SUBMITTER: Torres-Garcia W 

PROVIDER: S-EPMC4103589 | biostudies-literature | 2014 Aug

REPOSITORIES: biostudies-literature