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ABSTRACT: Objectives
To discuss the novel agents which are being developed for the treatment of advanced and recurrent endometrial carcinoma and to review other molecular targets that may be interesting in the treatment of this disease. While the majority of women with endometrial cancer enjoy a relatively good prognosis, the options for those women who suffer from a disease recurrence are limited and there is a need to identify novel agents.Methods
A review of clinical trials of novel therapeutic agents and their molecular targets is provided. In addition, a review of the current literature on other potential molecular targets for endometrial cancer was performed.Results
Several phase II trials of novel agents, both alone and in combination with traditional cytotoxic chemoth
SUBMITTER: Gehrig PA
PROVIDER: S-EPMC4103663 | biostudies-literature | 2010 Feb
REPOSITORIES: biostudies-literature