Patterns of statin initiation, intensification, and maximization among patients hospitalized with an acute myocardial infarction.

ABSTRACT:

Background

Intensive statins are superior to moderate statins in reducing morbidity and mortality after an acute myocardial infarction. Although studies have documented rates of statin prescription as a quality performance measure, variations in hospitals' rates of initiating, intensifying, and maximizing statin therapy after acute myocardial infarction are unknown.

Methods and results

We assessed statin use at admission and discharge among 4340 acute myocardial infarction patients from 24 US hospitals (2005-2008). Hierarchical models estimated site variation in statin initiation in naïve patients, intensification in those undergoing submaximal therapy, and discharge on maximal therapy (defined as a statin with expected low-density lipoprotein cholesterol lowering ≥ 50%) aft

SUBMITTER: Arnold SV 

PROVIDER: S-EPMC4103689 | biostudies-literature | 2014 Mar

REPOSITORIES: biostudies-literature