Randomized efficacy trial of two psychotherapies for depression in youth with inflammatory bowel disease.

ABSTRACT:

Objective

Pediatric inflammatory bowel disease (IBD) is associated with high rates of depression. This study compared the efficacy of cognitive behavioral therapy (CBT) to supportive nondirective therapy (SNDT) in treating youth with comorbid IBD and depression.

Method

Youth (51% female and 49% male; age 9-17 years, mean age 14.3 years) with depression and Crohn's disease (n = 161) or ulcerative colitis (n = 56) were randomly assigned to a 3-month course of CBT or SNDT. The primary outcome was comparative reduction in depressive symptom severity; secondary outcomes were depression remission, increase in depression response, and improved health-related adjustment and IBD activity.

Results

A total of 178 participants (82%) completed the 3-month intervention. Both psycho

SUBMITTER: Szigethy E 

PROVIDER: S-EPMC4104185 | biostudies-literature | 2014 Jul

REPOSITORIES: biostudies-literature