Challenges and opportunities for cancer vaccines in the current NSCLC clinical scenario.

ABSTRACT: This review is aimed to focus on NSCLC as an emerging and promising model for active immunotherapy and the challenges for its inclusion in the current clinical scenario. Cancer vaccines for NSCLC have been focused as a therapeutic option based on the identification of a tumor hallmark and the active immunization with the related molecules that triggers cellular and/or humoral responses that consequently destroy or delay the rate of malignant progression. This therapeutic intervention in an established disease state has been aimed to impact into prolonging patient´s survival with ethically accepted quality of life. Understanding of relationship between structure and function in cancer vaccines is essential to interpret their opportunities to impact into prolonging survival and increasing qu

SUBMITTER: Rodriguez PC 

PROVIDER: S-EPMC4104452 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature