Contrasting networks for recognition memory and recency memory revealed by immediate-early gene imaging in the rat.

ABSTRACT: The expression of the immediate-early gene c-fos was used to compare networks of activity associated with recency memory (temporal order memory) and recognition memory. In Experiment 1, rats were first familiarized with sets of objects and then given pairs of different, familiar objects to explore. For the recency test group, each object in a pair was separated by 110 min in the time between their previous presentations. For the recency control test, each object in a pair was separated by less than a 1 min between their prior presentations. Temporal discrimination of the objects correlated with c-fos activity in the recency test group in several sites, including area Te2, the perirhinal cortex, lateral entorhinal cortex, as well as the dentate gyrus, hippocampal fields CA3 and CA1. For bot

SUBMITTER: Olarte-Sanchez CM 

PROVIDER: S-EPMC4105319 | biostudies-literature | 2014 Aug

REPOSITORIES: biostudies-literature