Regulatory network rewiring for secondary metabolism in Arabidopsis thaliana under various conditions.

ABSTRACT:

Background

Plant secondary metabolites are critical to various biological processes. However, the regulations of these metabolites are complex because of regulatory rewiring or crosstalk. To unveil how regulatory behaviors on secondary metabolism reshape biological processes, we constructed and analyzed a dynamic regulatory network of secondary metabolic pathways in Arabidopsis.

Results

The dynamic regulatory network was constructed through integrating co-expressed gene pairs and regulatory interactions. Regulatory interactions were either predicted by conserved transcription factor binding sites (TFBSs) or proved by experiments. We found that integrating two data (co-expression and predicted regulatory interactions) enhanced the number of highly confident regulatory interac

SUBMITTER: Lv Q 

PROVIDER: S-EPMC4105546 | biostudies-literature | 2014 Jul

REPOSITORIES: biostudies-literature