Ontology highlight
ABSTRACT:
SUBMITTER: Somme J
PROVIDER: S-EPMC4105751 | biostudies-literature | 2014 Aug
REPOSITORIES: biostudies-literature
RNA (New York, N.Y.) 20140620 8
The 2'-O-methylation of the nucleoside at position 32 of tRNA is found in organisms belonging to the three domains of life. Unrelated enzymes catalyzing this modification in Bacteria (TrmJ) and Eukarya (Trm7) have already been identified, but until now, no information is available for the archaeal enzyme. In this work we have identified the methyltransferase of the archaeon Sulfolobus acidocaldarius responsible for the 2'-O-methylation at position 32. This enzyme is a homolog of the bacterial Tr ...[more]