A cohort analysis to identify eligible patients for intraoperative radiotherapy (IORT) of early breast cancer.

ABSTRACT:

Background

Since the results from the randomized TARGIT A trial were published, intraoperative radiotherapy (IORT) is used more often. IORT can be provided as accelerated partial breast irradiation (APBI) or as a boost. The definition of suitable patients for IORT as APBI differs between different national societies (e.g. ESTRO and ASTRO) and different inclusion criteria of trials and so does the eligibility of patients. This analysis identifies eligible patients for IORT according to available consensus statements and inclusion criteria of the ongoing TARGIT trials.

Methods

Between 01/03 - 12/09, 1505 breast cancer cases were treated at the breast cancer center at the University Medical Center Mannheim. Complete data sets for age, stage (T, N, and M), histology and hormone

SUBMITTER: Sperk E 

PROVIDER: S-EPMC4105865 | biostudies-literature | 2014 Jul

REPOSITORIES: biostudies-literature