Probiotic potential of Lactobacillus strains with antimicrobial activity against some human pathogenic strains.

ABSTRACT: The objective of this study was to isolate, identify, and characterize some lactic acid bacterial strains from human milk, infant feces, and fermented grapes and dates, as potential probiotics with antimicrobial activity against some human pathogenic strains. One hundred and forty bacterial strains were isolated and, after initial identification and a preliminary screening for acid and bile tolerance, nine of the best isolates were selected and further identified using 16 S rRNA gene sequences. The nine selected isolates were then characterized in vitro for their probiotic characteristics and their antimicrobial activities against some human pathogens. Results showed that all nine isolates belonged to the genus Lactobacillus. They were able to tolerate pH 3 for 3 h, 0.3% bile salts for 4 h

SUBMITTER: Shokryazdan P 

PROVIDER: S-EPMC4106073 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature