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Oral manifestations of hereditary nonpolyposis colorectal cancer syndrome: a family case series.


ABSTRACT:

Introduction

Hereditary nonpolyposis colorectal cancer is a colorectal cancer syndrome characterized by the development of colorectal cancer and extracolonic tumors, and this syndrome has an autosomal dominant mode of inheritance. To our knowledge, our study was the first to find dento-osseous anomalies and the second to observe Fordyce granules in a family with individuals with hereditary nonpolyposis colorectal cancer.

Case presentations

Twenty members of one Brazilian family with individuals with hereditary nonpolyposis colorectal cancer were analyzed according to the presence of colorectal cancer and the occurrence of Fordyce granules and dento-osseous anomalies. Their average age was 29.6 (range 7 to 53 years) years. Medical examinations of this family with hereditary n

SUBMITTER: Almeida FT 

PROVIDER: S-EPMC4106215 | biostudies-literature | 2014 Jul

REPOSITORIES: biostudies-literature