Characterization of the vaginal microbiota of healthy Canadian women through the menstrual cycle.

ABSTRACT:

Background

The vaginal microbial community plays a vital role in maintaining women's health. Understanding the precise bacterial composition is challenging because of the diverse and difficult-to-culture nature of many bacterial constituents, necessitating culture-independent methodology. During a natural menstrual cycle, physiological changes could have an impact on bacterial growth, colonization, and community structure. The objective of this study was to assess the stability of the vaginal microbiome of healthy Canadian women throughout a menstrual cycle by using cpn60-based microbiota analysis. Vaginal swabs from 27 naturally cycling reproductive-age women were collected weekly through a single menstrual cycle. Polymerase chain reaction (PCR) was performed to amplify the univer

SUBMITTER: Chaban B 

PROVIDER: S-EPMC4106219 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature