Maternal mRNA expression levels of H19 are inversely associated with risk of macrosomia.

ABSTRACT:

Introduction

To investigate the associations between the mRNA levels of H19 in term placenta and risk of macrosomia.

Material and methods

Term placentas were collected from 37 macrosomia and 37 matched neonates with normal birth weight (controls) born in Changzhou Women and Children Health Hospital, Jiangsu province, P. R. China from March 1 to June 30, 2008. The mRNA levels of H19 in those placentas were measured by real-time polymerase chain reaction (PCR). Simple and multiple logistic regression models were used to explore the risk factors in the development of macrosomia. All analyses were performed using Stata 10.0 (StataCorp, College Station, Texas, USA).

Results

The average H19 mRNA level of the macrosomia group was 1.450 ±0.456 while in the control group it wa

SUBMITTER: Jiang H 

PROVIDER: S-EPMC4107258 | biostudies-literature | 2014 Jun

REPOSITORIES: biostudies-literature