Non-inferiority of creatinine excretion rate to urinary L-FABP and NGAL as predictors of early renal allograft function.

ABSTRACT:

Background

We evaluated accuracy of urinary liver type fatty acid-binding protein (L-FABP) for prediction of early allograft function and compared it to neutrophil gelatinase associated lipocalin (NGAL), diuresis and urinary creatinine excretion rate (UCr).

Methods

Urine samples from 71 consecutive patients were taken 4, 10, 24 and 48 h after transplantation. We classified recipients into two groups: immediate graft function (IGF), with more than 70% reduction of serum Cr at 7th day post-transplant, and delayed graft function (DGF)/slow graft function (SGF) group (DGF--the need for hemodialysis procedure in the first week, SGF--less than 70% reduction of serum Cr in the first week).

Results

Thirty-one recipients had IGF and 40 had DGF/SGF. L-FABP was only useful 48 h

SUBMITTER: Pajek J 

PROVIDER: S-EPMC4107724 | biostudies-literature | 2014 Jul

REPOSITORIES: biostudies-literature