Childhood social disadvantage, cardiometabolic risk, and chronic disease in adulthood.

ABSTRACT: Adverse social environments in early life are hypothesized to become biologically embedded during the first few years of life, with potentially far-reaching implications for health across the life course. Using prospective data from a subset of a US birth cohort, the Collaborative Perinatal Project, started in 1959-1966 (n = 566), we examined associations of social disadvantage assessed in childhood with cardiometabolic function and chronic disease status more than 40 years later (in 2005-2007). Social disadvantage was measured with an index that combined information on adverse socioeconomic and family stability factors experienced between birth and age 7 years. Cardiometabolic risk (CMR) was assessed by combining information from 8 CMR biomarkers; an index of chronic disease status was de

SUBMITTER: Non AL 

PROVIDER: S-EPMC4108040 | biostudies-literature | 2014 Aug

REPOSITORIES: biostudies-literature