The effect of colostrum intake on blood plasma proteome profile in newborn lambs: low abundance proteins.

ABSTRACT:

Background

Colostrum intake by newborn lambs plays a fundamental role in the perinatal period, ensuring lamb survival. In this study, blood plasma samples from two groups of newborn lambs (Colostrum group and Delayed Colostrum group) at 2 and 14 h after birth were treated to reduce the content of high abundance proteins and analyzed using Two-Dimensional Differential in Gel Electrophoresis and MALDI MS/MS for protein identification in order to investigate low abundance proteins with immune function in newborn lambs.

Results

The results showed that four proteins were increased in the blood plasma of lambs due to colostrum intake. These proteins have not been previously described as increased in blood plasma of newborn ruminants by colostrum intake. Moreover, these proteins ha

SUBMITTER: Hernandez-Castellano LE 

PROVIDER: S-EPMC4108057 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature