Treatment of Asymptomatic Carriers of Plasmodium falciparum with Artemether-Lumefantrine: Impact on the Prevalence of Anemia.

ABSTRACT:

Introduction

An investigation of whether treatment of asymptomatic carriers of Plasmodium falciparum with artemether-lumefantrine (AL), in addition to the routine treatment of symptomatic cases with AL, could improve the prevalence of anemia in 18 villages in Burkina Faso.

Methods

This was a single-center, controlled, parallel, cluster-randomized study to evaluate the effect of systematic treatment of P. falciparum asymptomatic carriers at a community level on hemoglobin (Hb) levels and anemic status of children (<5 years) and adults during four screening campaigns carried out over a 12-month period, compared with no treatment of asymptomatic carriers.

Results

The change in Hb level in all asymptomatic carriers aged >6 months from Day 1 to Day 28 of the first campaign

SUBMITTER: Tiono AB 

PROVIDER: S-EPMC4108097 | biostudies-literature | 2013 Jun

REPOSITORIES: biostudies-literature