Common versus psychopathology-specific risk factors for psychotic experiences and depression during adolescence.

ABSTRACT:

Background

An argument often used to support the view that psychotic experiences (PEs) in general population samples are a valid phenotype for studying the aetiology of schizophrenia is that risk factors for schizophrenia show similar patterns of association with PEs. However, PEs often co-occur with depression, and no study has explicitly tested whether risk factors for schizophrenia are shared between PEs and depression, or are psychopathology specific, while jointly modelling both outcomes.

Method

We used data from 7030 subjects from a birth cohort study. Depression and PEs at age 18 years were assessed using self-report questionnaires and semi-structured interviews. We compared the extent to which risk factors for schizophrenia across sociodemographic, familial, neurodev

SUBMITTER: Kounali D 

PROVIDER: S-EPMC4108252 | biostudies-literature | 2014 Sep

REPOSITORIES: biostudies-literature