Transferrin saturation ratio and risk of total and cardiovascular mortality in the general population.

ABSTRACT:

Background

The transferrin saturation (TSAT) ratio is a commonly used indicator of iron deficiency and iron overload in clinical practice but precise relationships with total and cardiovascular mortality are unclear.

Purpose

To better understand this relationship, we explored the association of TSAT ratio (serum iron/total iron binding capacity) with mortality in the general population.

Methods

The relationships of TSAT ratio with total and cardiovascular mortality were explored in 15 823 subjects age 20 and older from the Third National Health and Nutrition Examination Survey (1988-94). All subjects had vital status assessed through to 2006.

Results

During follow-up, 9.7% died of which 4.4% were from cardiovascular disease. In unadjusted analysis, increasing T

SUBMITTER: Stack AG 

PROVIDER: S-EPMC4108849 | biostudies-literature | 2014 Aug

REPOSITORIES: biostudies-literature