Evolving BioAssay Ontology (BAO): modularization, integration and applications.

ABSTRACT: The lack of established standards to describe and annotate biological assays and screening outcomes in the domain of drug and chemical probe discovery is a severe limitation to utilize public and proprietary drug screening data to their maximum potential. We have created the BioAssay Ontology (BAO) project (http://bioassayontology.org) to develop common reference metadata terms and definitions required for describing relevant information of low-and high-throughput drug and probe screening assays and results. The main objectives of BAO are to enable effective integration, aggregation, retrieval, and analyses of drug screening data. Since we first released BAO on the BioPortal in 2010 we have considerably expanded and enhanced BAO and we have applied the ontology in several internal and exte

SUBMITTER: Abeyruwan S 

PROVIDER: S-EPMC4108877 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature